Scalable Content-centric Routing for Hybrid ICN

Hybrid Information-Centric Networking (hICN) is an incrementally-deployable information-centric networking architecture that is built on top of IPv6. In hICN, application-level identifiers are directly used to route interest packets (i.e., request for content) to fetch a copy of the desired content/data from any location. However, following the Internet Protocol conventions that require storing pre-computed routing/forwarding state for all prefixes in the routers raises scalability concerns, especially at the inter-domain level. Here we consider instead the other extreme; i.e. on-demand routing computation for content name prefixes when interest packets arrive at the router. Following this approach, we propose a centralized routing service within a domain that keeps a mapping between hICN name prefixes and locators (i.e., routable addresses) to hICN routers. Once a locator is received, an hICN router forwards an interest packet towards the intended destination using segment routing. We evaluated the proposed solution through a real testbed implementation in order to demonstrate that the performance is equivalent to typical hICN forwarding, while offering a scalability solution

Information-Centric Connectivity

Mobile devices are often presented with multiple connectivity options usually making a selection either randomly or based on load/wireless conditions metrics, as is the case of current offloading schemes. In this paper we claim that link-layer connectivity can be associated with information-availability and in this respect connectivity decisions should be information-aware. This constitutes a next step for the Information-Centric Networking paradigm, realizing the concept of Information-Centric Connectivity (ICCON). We elaborate on different types of information availability and connectivity decisions in the context of ICCON, present specific use cases and discuss emerging opportunities, challenges and technical approaches. We illustrate the potential benefits of ICCON through preliminary simulation and numerical results in an example use case

Characterisation of age and polarity at onset in bipolar disorder

Background Studying phenotypic and genetic characteristics of age at onset (AAO) and polarity at onset (PAO) in bipolar disorder can provide new insights into disease pathology and facilitate the development of screening tools. Aims To examine the genetic architecture of AAO and PAO and their association with bipolar disorder disease characteristics. Method Genome-wide association studies (GWASs) and polygenic score (PGS) analyses of AAO (n = 12 977) and PAO (n = 6773) were conducted in patients with bipolar disorder from 34 cohorts and a replication sample (n = 2237). The association of onset with disease characteristics was investigated in two of these cohorts. Results Earlier AAO was associated with a higher probability of psychotic symptoms, suicidality, lower educational attainment, not living together and fewer episodes. Depressive onset correlated with suicidality and manic onset correlated with delusions and manic episodes. Systematic differences in AAO between cohorts and continents of origin were observed. This was also reflected in single-nucleotide variant-based heritability estimates, with higher heritabilities for stricter onset definitions. Increased PGS for autism spectrum disorder (β = −0.34 years, s.e. = 0.08), major depression (β = −0.34 years, s.e. = 0.08), schizophrenia (β = −0.39 years, s.e. = 0.08), and educational attainment (β = −0.31 years, s.e. = 0.08) were associated with an earlier AAO. The AAO GWAS identified one significant locus, but this finding did not replicate. Neither GWAS nor PGS analyses yielded significant associations with PAO. Conclusions AAO and PAO are associated with indicators of bipolar disorder severity. Individuals with an earlier onset show an increased polygenic liability for a broad spectrum of psychiatric traits. Systematic differences in AAO across cohorts, continents and phenotype definitions introduce significant heterogeneity, affecting analyses

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc

Scalable Content-centric Routing for Hybrid ICN

Hybrid Information-Centric Networking (hICN) is an incrementally-deployable information-centric networking architecture that is built on top of IPv6. In hICN, application-level identifiers are directly used to route interest packets (i.e., request for content) to fetch a copy of the desired content/data from any location. However, following the Internet Protocol conventions that require storing pre-computed routing/forwarding state for all prefixes in the routers raises scalability concerns, especially at the inter-domain level. Here we consider instead the other extreme; i.e. on-demand routing computation for content name prefixes when interest packets arrive at the router. Following this approach, we propose a centralized routing service within a domain that keeps a mapping between hICN name prefixes and locators (i.e., routable addresses) to hICN routers. Once a locator is received, an hICN router forwards an interest packet towards the intended destination using segment routing. We evaluated the proposed solution through a real testbed implementation in order to demonstrate that the performance is equivalent to typical hICN forwarding, while offering a scalability solution

Multipath TCP Architecture for Infotainment Multimedia Applications in Vehicular Networks

International audienceThe large deployment of Internet resources has facilitated the accelerated development of Intelligent Transport Systems (ITS) including a large diversity of distributed applications such as non-safety infotainment vehicular applications. In vehicular networks, nodes can connect to Internet using Road Side Units (RSUs), but the complete deployment of RSUs along all the transport network seems unfeasible. So, we can take advantage of multihomed devices using complementary access network technologies, such as satellite networks, in order to maintain the connectivity. Several solutions have been implemented in order to take advantage of multihoming and multipath capabilities of mobile nodes. However, in dynamic network scenarios involving multipath communication channels, the QoS requirements of these applications is not always globally managed and guaranteed. Moreover, specific multimedia semantics of the transmitted data is not usually considered by the available transmission mechanisms and protocols. In this work, we present a Multipath TCP communication architecture that take full advantage of the intrinsic multimedia QoS semantics based in Deep Packet Inspection in order to self-manage the available resources and to provide a more compliant e2e transport service

Data Availability Sampling in Ethereum: Analysis of P2P Networking Requirements

Despite their increasing popularity, blockchains still suffer from severe scalability limitations. Recently, Ethereum proposed a novel approach to block validation based on Data Availability Sampling (DAS), that has the potential to improve its transaction per second rate by more than two orders of magnitude. DAS should also significantly reduce per-transaction validation costs. At the same time, DAS introduces new communication patterns in the Ethereum peer-to-peer (P2P) network. These drastically increase the amount of exchanged data and impose stringent latency objectives. In this paper, we review the new requirements for P2P networking associated with DAS, discuss open challenges, and identify new research directions